Some nights, cooking dinner feels like a never-ending chore—especially when you’re trying to keep it healthy, satisfying, and family-friendly. But what if you could whip up a meal that’s packed with protein, low in carbs, and practically takes care of itself?
Enter the casserole: the ultimate fuss-free dinner solution. With just a few ingredients and minimal prep, you can create a hearty, delicious dish that fuels your body and leaves you with leftovers for the next day.
Ready to make dinnertime easier and tastier? Here are some of my favorite low-carb, high-protein casserole ideas to keep you on track without the hassle!
1. Philly Cheesesteak Casserole

This Philly Cheesesteak Casserole is a mouthwatering dinner option that’s rich, cheesy, and surprisingly healthy.
It’s easy to prepare with simple ingredients and minimal effort—perfect for a low-carb twist on a classic favorite.
Per Serving:
- Calories: 415
- Fats: 33g
- Protein: 25g
- Carbs: 5g
2. Keto Chicken Cauliflower Casserole

This casserole combines succulent chicken, savory cauliflower, and crispy bacon, all coated in a luscious, creamy sauce.
Need I say more? It’s a crowd-pleaser that satisfies your cravings while keeping carbs at bay.
The best part? It’s effortlessly adaptable — perfect for those on a low-carb diet, yet easily tweaked so everyone at the table can enjoy it.
Per Serving:
- Calories: 342
- Fats: 27g
- Protein: 21g
- Carbs: 4.6g
3. Mushroom Cheeseburger Casserole

With just 7 ingredients, this low-carb, keto-friendly casserole transforms the classic mushroom Swiss burger into a comforting dish, containing only 6g net carbs per serving.
The rich, savory blend of mushrooms and ground beef pairs perfectly with the bold, tangy notes of goat cheese, making it a dinner favorite for any crowd.
Per Serving:
- Calories: 540
- Fats: 35g
- Protein: 45g
- Carbs: 6.5g
4. Chicken Cordon Bleu Casserole

This keto chicken cordon bleu casserole is a quick and easy recipe, packed with tender chicken, gooey melted cheese, and savory diced ham.
It’s the perfect go-to meal for busy weeknights, sure to satisfy the whole family!
Per Serving:
- Calories: 408
- Fats: 30g
- Protein: 30g
- Carbs: 2g
5. Hatch Chile Rellenos Casserole

Chiles are layered with a blend of two cheeses and baked to perfection. This recipe serves 6 to 8, depending on whether it’s enjoyed as a main course, side dish, or a hearty breakfast casserole.
Per Serving:
- Calories: 303
- Fats: 23g
- Protein: 16g
- Carbs: 7g
6. Keto Tuna Casserole

This keto tuna casserole is a tasty and wholesome dish made with naturally low-carb ingredients.
With just 3g of net carbs per serving, it’s rich, cheesy, and satisfying — an ideal choice for a cozy weeknight dinner.
Per Serving:
- Calories: 304
- Fats: 21g
- Protein: 23g
- Carbs: 4g
7. Keto Reuben Casserole

The Keto Reuben Casserole brings together all the classic flavors you love in a quick and easy 30-minute meal.
Layers of corned beef, tangy sauerkraut, creamy special sauce, and melted Swiss cheese create a hearty, family-friendly dinner.
Per Serving:
- Calories: 407
- Fats: 26g
- Protein: 29g
- Carbs: 4g
8. Sausage and Spinach Breakfast Casserole

Let’s start with one of my favorite casserole recipes — a classic blend of sausage and spinach. While it’s perfect for breakfast, it’s satisfying enough to enjoy any time of day.
It’s ideal for feeding a crowd and works wonderfully for meal prep, staying fresh in the fridge for days.
Per Serving:
- Calories: 407
- Fats: 31g
- Protein: 23g
- Carbs: 8.1g
9. Roasted Poblano & Chorizo Egg Casserole

The Poblano & Chorizo Egg Casserole is a flavorful, low-carb breakfast dish that’s great for brunch or even dinner!
It features fire-roasted peppers layered with zesty chorizo and a blend of Mexican cheeses, creating a hearty egg bake packed with bold, vibrant flavors.
Per Serving:
- Calories: 290
- Fats: 21g
- Protein: 19g
- Carbs: 8g
10. Million Dollar Chicken Casserole

This Million Dollar Chicken casserole is the ultimate comfort food. With just a handful of simple ingredients, it comes together in no time.
Tender chicken breast is layered with a rich, cheesy sauce and crispy bacon, then baked to perfection — juicy, creamy, and irresistible.
Per Serving:
- Calories: 590
- Fats: 43
- Protein: 46g
- Carbs: 3g
11. Keto Taco Casserole

Everyone deserves a delicious taco night, even without the carbs. Thankfully, this low-carb, high-protein casserole offers a simple and speedy way to savor all those classic taco flavors—no shell required.
In just 45 minutes, you’ll have a protein-packed casserole that’s perfect for leftovers.
Per Serving:
- Calories: 568
- Fats: 40g
- Protein: 37g
- Carbs: 14g
- Fiber: 4.6g
12. Broccoli Cauliflower Casserole

Cauliflower and broccoli are two of my go-to veggies for low-carb cooking, and this casserole is no exception.
Packed with 17g of protein per serving, it’s a deliciously satisfying dish that’s hard to resist — trust me, I know!
Per Serving:
- Calories: 388
- Fats: 32g
- Protein: 17g
- Carbs: 12g
13. Spinach Artichoke Chicken Casserole

This ultra-cheesy Spinach Artichoke Chicken Casserole takes inspiration from the classic dip, transforming it into a hearty 30-minute meal with extra vegetables and a boost of protein.
It’s perfect for a low-carb dinner, so don’t forget to save this recipe for later!
Per Serving:
- Calories: 530
- Fats: 44g
- Protein: 27g
- Carbs: 5g
14. Leftover Pulled Pork Cuban Casserole

Don’t let that leftover pulled pork go to waste! Turn it into a mouthwatering Cuban casserole.
With layers of tender pork, melted cheese, crispy bacon, and tangy pickles, this dish captures the classic flavors of a Cuban sandwich.
Quick, easy, and packed with protein — it’s the perfect way to reinvent your leftovers.
Per Serving:
- Calories: 413
- Fats: 26g
- Protein: 41g
- Carbs: 2g
15. Keto Mexican Chicken Casserole

Here’s a fresh take on a Mexican casserole, topped with a gooey layer of melted cheese for that extra touch of indulgence.
Packed with comforting flavors, it’s sure to become a family favorite. The best part? You can easily tailor the ingredients to whatever you have on hand.
Per Serving:
- Calories: 299
- Fats: 17g
- Protein: 29g
- Carbs: 8g